The impact of postoperative packing of perianal abscess cavities: a multicentre randomised controlled trial (PPAC2)
Study area: Colorectal
Aim: The aim is to compare internal wound packing to no packing in postoperative management following incision and drainage of perianal abscess
Who can participate: Patients aged 18 years and over undergoing incision and drainage of a primary perianal abscess cavity
The clinical and cost effectiveness of surgical interventions for stones in the lower pole of the kidney: The Percutaneous nephrolithotomy, flexible Ureterorenoscopy and Extracorporeal shockwave lithotripsy for lower pole kidney stones Randomised Controlled Trial (PUrE RCT)
Study area: Surgical
Aim: To find which of the three standard surgical treatments for removal of lower pole kidney stones is most clinically and cost effective, dependant on the size of the kidney stone.
Who can participate: Men and women aged over 16 with a stone (or stones) in the lower pole of either kidney.
A randomised double-blind controlled phase III study to compare the efficacy and safety of intravenous ferric carboxymaltose with placebo in patients with anaemia undergoing major open abdominal surgery
Study Area: Surgical
Aim: To determine if a single dose of intravenous iron administered to patients with anaemia prior to major surgery reduces the need for peri-operative blood transfusion. Also to evaluate the effect of intravenous ferric iron compared with placebo on health related quality of life, post-operative morbidity, safety and length of hospital stay
Who can participate: Men and women aged over 18 who are planned for an elective open abdominal surgery and have been found to be anaemic (Haemoglobin blood test result between 130-90 g/L for men and 120-90 g/L for women).