Surgery Studies

The impact of postoperative packing of perianal abscess cavities: a multicentre randomised controlled trial (PPAC2)

Study area: Colorectal

Aim: The aim is to compare internal wound packing to no packing in postoperative management following incision and drainage of perianal abscess

Who can participate: Patients aged 18 years and over undergoing incision and drainage of a primary perianal abscess cavity 


The clinical and cost effectiveness of surgical interventions for stones in the lower pole of the kidney: The Percutaneous nephrolithotomy, flexible Ureterorenoscopy and Extracorporeal shockwave lithotripsy for lower pole kidney stones Randomised Controlled Trial (PUrE RCT) 

Study area: Surgical

Aim: To find which of the three standard surgical treatments for removal of lower pole kidney stones is most clinically and cost effective, dependant on the size of the kidney stone.

Who can participate: Men and women aged over 16 with a stone (or stones) in the lower pole of either kidney.


A randomised double-blind controlled phase III study to compare the efficacy and safety of intravenous ferric carboxymaltose with placebo in patients with anaemia undergoing major open abdominal surgery 

Study Area: Surgical 

Aim: To determine if a single dose of intravenous iron administered to patients with anaemia prior to major surgery reduces the need for peri-operative blood transfusion. Also to evaluate the effect of intravenous ferric iron compared with placebo on health related quality of life, post-operative morbidity, safety and length of hospital stay 

Who can participate: Men and women aged over 18 who are planned for an elective open abdominal surgery and have been found to be anaemic (Haemoglobin blood test result  between 130-90 g/L for men and 120-90 g/L for women).

If you would like any further information on the following studies, and to find out if you are eligible please contact:


Address: R&D office, C254, West Wing, Broomfield Hospital, Court Road, Chelmsford, Essex, CM1 7ET 

Telephone01245 515136
Email: Research@meht.nhs.uk